EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
    1.1.1.100 | Polycystic Kidney Diseases |
19924289 |
A C. elegans model for mitochondrial fatty acid synthase II: the longevity-associated gene W09H1.5/mecr-1 encodes a 2-trans-enoyl-thioester reductase. |
causal interaction
unassigned |
2
0 |
| 1.1.1.100 | Tuberculosis |
29946302 |
Advance in Research on Mycobacterium tuberculosis FabG4 and Its Inhibitor. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
2
4
0 |
| 1.1.1.100 | Tuberculosis |
21081168 |
Crystal structure of FabG4 from Mycobacterium tuberculosis reveals the importance of C-terminal residues in ketoreductase activity. |
ongoing research
unassigned |
3
0 |
| 1.1.1.100 | Tuberculosis |
23163771 |
Crystal structure of hexanoyl-CoA bound to ?-ketoacyl reductase FabG4 of Mycobacterium tuberculosis. |
ongoing research
unassigned |
1
0 |
| 1.1.1.100 | Tuberculosis |
22750865 |
Crystallization and preliminary X-ray diffraction analysis of the high molecular weight ketoacyl reductase FabG4 complexed with NADH. |
unassigned |
0 |
| 1.1.1.100 | Tuberculosis |
26092447 |
Design, synthesis and characterization of dual inhibitors against new targets FabG4 and HtdX of Mycobacterium tuberculosis. |
therapeutic application
unassigned |
4
0 |
| 1.1.1.100 | Tuberculosis |
24129589 |
Design, synthesis and characterization of novel inhibitors against mycobacterial ?-ketoacyl CoA reductase FabG4. |
therapeutic application
unassigned |
3
0 |
| 1.1.1.100 | Tuberculosis |
17337570 |
Functional complementation of the essential gene fabG1 of Mycobacterium tuberculosis by Mycobacterium smegmatis fabG but not Escherichia coli fabG. |
therapeutic application
unassigned |
1
0 |
| 1.1.1.100 | Tuberculosis |
14693546 |
In vitro inhibition of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA by isoniazid. |
unassigned |
0 |
| 1.1.1.100 | Latent Infection |
25666821 |
Inhibition of M. tuberculosis ?-ketoacyl CoA reductase FabG4 (Rv0242c) by triazole linked polyphenol-aminobenzene hybrids: Comparison with the corresponding gallate counterparts. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
