EC Number   |
Disease |
PubMed ID  |
Title of Publication |
Category |
Confidence Level |
|---|
    1.1.1.100 | Tuberculosis |
14693546 |
In vitro inhibition of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA by isoniazid. |
unassigned |
0 |
| 1.1.1.100 | Tuberculosis |
14766307 |
Selection of an Escherichia coli host that expresses mutant forms of Mycobacterium tuberculosis 2-trans enoyl-ACP(CoA) reductase and 3-ketoacyl-ACP(CoA) reductase enzymes. |
ongoing research
therapeutic application
unassigned |
2
3
0 |
| 1.1.1.100 | Tuberculosis |
15977159 |
Ligand-induced fit in mycobacterial MabA: the sequence-specific C-terminus locks the conformational change. |
unassigned |
0 |
| 1.1.1.100 | Tuberculosis |
17337570 |
Functional complementation of the essential gene fabG1 of Mycobacterium tuberculosis by Mycobacterium smegmatis fabG but not Escherichia coli fabG. |
therapeutic application
unassigned |
1
0 |
| 1.1.1.100 | Tuberculosis |
18155153 |
Mycobacterium tuberculosis beta-ketoacyl-ACP reductase: alpha-secondary kinetic isotope effects and kinetic and equilibrium mechanisms of substrate binding. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 1.1.1.100 | Polycystic Kidney Diseases |
19924289 |
A C. elegans model for mitochondrial fatty acid synthase II: the longevity-associated gene W09H1.5/mecr-1 encodes a 2-trans-enoyl-thioester reductase. |
causal interaction
unassigned |
2
0 |
| 1.1.1.100 | Tuberculosis |
20178986 |
Phosphorylation of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA regulates mycolic acid biosynthesis. |
ongoing research
unassigned |
1
0 |
| 1.1.1.100 | Tuberculosis |
21081168 |
Crystal structure of FabG4 from Mycobacterium tuberculosis reveals the importance of C-terminal residues in ketoreductase activity. |
ongoing research
unassigned |
3
0 |
| 1.1.1.100 | Tuberculosis |
22750865 |
Crystallization and preliminary X-ray diffraction analysis of the high molecular weight ketoacyl reductase FabG4 complexed with NADH. |
unassigned |
0 |
| 1.1.1.100 | Tuberculosis |
23163771 |
Crystal structure of hexanoyl-CoA bound to ?-ketoacyl reductase FabG4 of Mycobacterium tuberculosis. |
ongoing research
unassigned |
1
0 |
