EC Number   |
Disease  |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.7.12.2 | Achondroplasia |
25387261 |
C-type natriuretic Peptide plasma levels are elevated in subjects with achondroplasia, hypochondroplasia, and thanatophoric dysplasia. |
causal interaction
unassigned |
3
0 |
| 2.7.12.2 | Acidosis |
22685289 |
Acidosis Promotes Bcl-2 Family-mediated Evasion of Apoptosis: INVOLVEMENT OF ACID-SENSING G PROTEIN-COUPLED RECEPTOR GPR65 SIGNALING TO MEK/ERK. |
therapeutic application
unassigned |
1
0 |
| 2.7.12.2 | Acneiform Eruptions |
31604105 |
A retrospective chart review on oral retinoids as a treatment for epidermal growth factor receptor inhibitor- and mitogen-activated protein kinase kinase inhibitor-induced acneiform eruptions. |
causal interaction
therapeutic application
unassigned |
1
4
0 |
| 2.7.12.2 | Acute Kidney Injury |
15673293 |
MEK inhibitor, U0126, attenuates cisplatin-induced renal injury by decreasing inflammation and apoptosis. |
causal interaction
ongoing research
unassigned |
1
3
0 |
| 2.7.12.2 | Acute Lung Injury |
20562902 |
Protective effects of luteolin against lipopolysaccharide-induced acute lung injury involves inhibition of MEK/ERK and PI3K/Akt pathways in neutrophils. |
ongoing research
therapeutic application
unassigned |
2
3
0 |
| 2.7.12.2 | Acute Lung Injury |
34159337 |
Discovery of pan-ErbB inhibitors protecting from SARS-CoV-2 replication, inflammation, and lung injury by a drug repurposing screen. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
1
2
0 |
| 2.7.12.2 | Adenocarcinoma |
10980611 |
Extracellular regulated kinase (ERK)-dependent regulation of sialomucin complex/rat Muc4 in mammary epithelial cells. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 2.7.12.2 | Adenocarcinoma |
16492916 |
Claudin-4, mitogen-activated protein kinase kinase 4, and stratifin are markers of gastric adenocarcinoma precursor lesions. |
diagnostic usage
ongoing research
unassigned |
3
3
0 |
| 2.7.12.2 | Adenocarcinoma |
21989899 |
Expression of EGFR, HER2, Phosphorylated ERK and Phosphorylated MEK in Colonic Neoplasms of Familial Adenomatous Polyposis Patients. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
4
4
0 |
| 2.7.12.2 | Adenocarcinoma |
22135231 |
Coexistence of PIK3CA and other oncogene mutations in lung adenocarcinoma-rationale for comprehensive mutation profiling. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
2
3 |
