EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   6.2.1.64 | Squamous Cell Carcinoma of Head and Neck |
28838998 |
The Neddylation Inhibitor Pevonedistat (MLN4924) Suppresses and Radiosensitizes Head and Neck Squamous Carcinoma Cells and Tumors. |
therapeutic application
unassigned |
3
0 |
| 6.2.1.64 | Squamous Cell Carcinoma of Head and Neck |
30341788 |
The Nedd8-activating enzyme inhibitor MLN4924 (TAK-924/Pevonedistat) induces apoptosis via c-Myc-Noxa axis in head and neck squamous cell carcinoma. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
1
3
3
2 |
| 6.2.1.64 | Stomach Neoplasms |
34258028 |
A Phase I study of pevonedistat plus capecitabine plus oxaliplatin in patients with advanced gastric cancer refractory to platinum (NCCH-1811). |
therapeutic application
unassigned |
4
0 |
| 6.2.1.64 | Xeroderma Pigmentosum |
33381997 |
Spironolactone-induced XPB degradation requires TFIIH integrity and ubiquitin-selective segregase VCP/p97. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
