EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.22.61 | Adenocarcinoma |
15645141 |
Adenovirus-mediated gene transfer of caspase-8 sensitizes human adenocarcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
4
0 |
| 3.4.22.61 | Adenocarcinoma |
17350814 |
beta-Sitosterol activates Fas signaling in human breast cancer cells. |
ongoing research
unassigned |
4
0 |
| 3.4.22.61 | Adenocarcinoma |
18675507 |
Short hairpin RNA targeting c-FLIP sensitizes human cervical adenocarcinoma Hela cells to chemotherapy and radiotherapy. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
3
3
0 |
| 3.4.22.61 | Adenocarcinoma |
18716417 |
Clinicopathological significance of caspase-8 and caspase-10 expression in rectal cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
1 |
| 3.4.22.61 | Adenocarcinoma |
19122287 |
3-Oxoolean-12-en-27-oic acid isolated from Aceriphyllum rossii induces caspase-8-dependent apoptosis in human promyelocytic leukemia HL-60 cells. |
unassigned |
0 |
| 3.4.22.61 | Adenocarcinoma |
19843670 |
Association of Breast Cancer Susceptibility Variants with Risk of Pancreatic Cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
3
2 |
| 3.4.22.61 | Adenocarcinoma |
22199128 |
Immunohistochemical analysis of cell death pathways in gastrointestinal adenocarcinoma. |
ongoing research
unassigned |
3
0 |
| 3.4.22.61 | Adenocarcinoma |
22922291 |
Tumor Necrosis Factor ? Stimulates Her-2 Cleavage by Activated Caspase-8. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
2
4
0 |
| 3.4.22.61 | Adenocarcinoma |
23470529 |
Upregulation of c-FLIP-short in response to TRAIL promotes survival of NSCLC cells, which could be suppressed by inhibition of Ca(2+)/calmodulin signaling. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
1
2
0 |
| 3.4.22.61 | Adenocarcinoma |
24509146 |
CpG island methylation of the MLH1, MGMT, DAPK, and CASP8 genes in cancerous and adjacent noncancerous stomach tissues. |
diagnostic usage
ongoing research
unassigned |
4
2
0 |
