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EC Number Disease PubMed ID Title of Publication Category Confidence Level
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61Virus Diseases 30261686 Apoptosis Induction by dsRNA-Dependent Protein Kinase R (PKR) in EPC Cells via Caspase 8 and 9 Pathways. causal interaction
unassigned
3
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61Virus Diseases 33568512 Porcine Epidemic Diarrhea Virus Infection Induces Caspase-8 mediated G3BP1 Cleavage and Subverts Stress Granules to Promote Viral Replication. causal interaction
unassigned
1
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61Whooping Cough 20004081 Butyrate and propionate induced activated or non-activated neutrophil apoptosis via HDAC inhibitor activity but without activating GPR-41/GPR-43 pathways. ongoing research
therapeutic application
unassigned
4
4
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61Wilms Tumor 14555992 Multigene methylation analysis of Wilms' tumour and adult renal cell carcinoma. diagnostic usage
unassigned
1
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61Wilms Tumor 14735202 SLIT2 promoter methylation analysis in neuroblastoma, Wilms' tumour and renal cell carcinoma. diagnostic usage
ongoing research
therapeutic application
unassigned
1
1
1
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61Yersinia Infections 27737018 Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death. causal interaction
therapeutic application
unassigned
2
1
0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61Yersinia Infections 30381458 Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection. unassigned 0
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61Zika Virus Infection 33536166 Zika virus infection induced apoptosis by modulating the recruitment and activation of pro-apoptotic protein Bax. unassigned 0
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