EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.21.B26 | Cardiovascular Diseases |
21681612 |
Inactivation of endothelial proprotein convertase 5/6 decreases collagen deposition in the cardiovascular system: role of fibroblast autophagy. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 3.4.21.B26 | Colonic Neoplasms |
21094132 |
Galectin-3 binding protein promotes cell motility in colon cancer by stimulating the shedding of protein tyrosine phosphatase kappa by proprotein convertase 5. |
diagnostic usage
unassigned |
1
0 |
| 3.4.21.B26 | Endometrial Neoplasms |
22390935 |
Proprotein convertases in post-menopausal endometrial cancer: Distinctive regulation and non-invasive diagnosis. |
causal interaction
diagnostic usage
ongoing research
unassigned |
2
1
2
0 |
| 3.4.21.B26 | Esophageal Atresia |
28446132 |
Pcsk5 is required in the early cranio-cardiac mesoderm for heart development. |
unassigned |
0 |
| 3.4.21.B26 | Infections |
19995186 |
The role of furin in papillomavirus infection. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 3.4.21.B26 | Influenza in Birds |
33820827 |
Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza. |
causal interaction
unassigned |
1
0 |
| 3.4.21.B26 | Nasal Polyps |
25350918 |
Proprotein Convertase 5/6A is Associated with BMP-2-induced Squamous Cell Differentiation. |
unassigned |
0 |
| 3.4.21.B26 | Neoplasm Metastasis |
24818756 |
Implications of Proprotein Convertases in Ovarian Cancer Cell Proliferation and Tumor Progression: Insights for PACE4 as a Therapeutic Target. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
2
4 |
| 3.4.21.B26 | Neoplasm Metastasis |
29161592 |
Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer. |
therapeutic application
unassigned |
1
0 |
| 3.4.21.B26 | Neoplasms |
19737405 |
The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
1
0 |
