EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    2.6.1.16 | Glioblastoma |
30771196 |
Mammalian Target of Rapamycin 2 (MTOR2) and C-MYC Modulate Glucosamine-6-Phosphate Synthesis in Glioblastoma (GBM) Cells Through Glutamine: Fructose-6-Phosphate Aminotransferase 1 (GFAT1). |
causal interaction
ongoing research
unassigned |
4
1
0 |
| 2.6.1.16 | Glioblastoma |
31414301 |
Correction to: Mammalian Target of Rapamycin 2 (MTOR2) and C-MYC Modulate Glucosamine-6-Phosphate Synthesis in Glioblastoma (GBM) Cells Through Glutamine: Fructose-6-Phosphate Aminotransferase 1 (GFAT1). |
ongoing research
unassigned |
1
0 |
| 2.6.1.16 | Glioma |
30771196 |
Mammalian Target of Rapamycin 2 (MTOR2) and C-MYC Modulate Glucosamine-6-Phosphate Synthesis in Glioblastoma (GBM) Cells Through Glutamine: Fructose-6-Phosphate Aminotransferase 1 (GFAT1). |
causal interaction
ongoing research
unassigned |
4
1
0 |
| 2.6.1.16 | Glucose Intolerance |
11118009 |
Overexpression of glutamine: fructose-6-phosphate amidotransferase in the liver of transgenic mice results in enhanced glycogen storage, hyperlipidemia, obesity, and impaired glucose tolerance. |
causal interaction
ongoing research
unassigned |
3
1
0 |
| 2.6.1.16 | glutamine-fructose-6-phosphate transaminase (isomerizing) deficiency |
29395675 |
Congenital myasthenic syndromes in Turkey: Clinical clues and prognosis with long term follow-up. |
causal interaction
unassigned |
4
0 |
| 2.6.1.16 | glutamine-fructose-6-phosphate transaminase (isomerizing) deficiency |
29905857 |
GFPT1 deficiency in muscle leads to myasthenia and myopathy in mice. |
causal interaction
unassigned |
2
0 |
| 2.6.1.16 | glutamine-fructose-6-phosphate transaminase (isomerizing) deficiency |
32286306 |
Chronic activation of hexosamine biosynthesis in the heart triggers pathological cardiac remodeling. |
causal interaction
unassigned |
4
0 |
| 2.6.1.16 | glutamine-fructose-6-phosphate transaminase (isomerizing) deficiency |
32615907 |
Drosophila GFAT1 and GFAT2 enzymes encode obligate developmental functions. |
unassigned |
0 |
| 2.6.1.16 | Glycogen Storage Disease Type II |
26501342 |
Global N-linked Glycosylation is Not Significantly Impaired in Myoblasts in Congenital Myasthenic Syndromes Caused by Defective Glutamine-Fructose-6-Phosphate Transaminase 1 (GFPT1). |
causal interaction
ongoing research
therapeutic application
unassigned |
1
2
1
0 |
| 2.6.1.16 | Hyperglycemia |
10997922 |
Overexpression of GFAT activates PAI-1 promoter in mesangial cells. |
unassigned |
0 |
