EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.1.1.57 | COVID-19 |
33080218 |
SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses. |
diagnostic usage
ongoing research
unassigned |
2
2
0 |
| 2.1.1.57 | COVID-19 |
33685335 |
In silico identification of novel SARS-COV-2 2'-O-methyltransferase (nsp16) inhibitors: structure-based virtual screening, molecular dynamics simulation and MM-PBSA approaches. |
causal interaction
therapeutic application
unassigned |
1
4
0 |
| 2.1.1.57 | COVID-19 |
34540874 |
Whole Genome Sequencing of SARS-CoV-2 Strains in COVID-19 Patients From Djibouti Shows Novel Mutations and Clades Replacing Over Time. |
unassigned |
0 |
| 2.1.1.57 | Dengue |
15152003 |
A structural basis for the inhibition of the NS5 dengue virus mRNA 2'-O-methyltransferase domain by ribavirin 5'-triphosphate. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
| 2.1.1.57 | Dengue |
17259217 |
High-yield production of short GpppA- and 7MeGpppA-capped RNAs and HPLC-monitoring of methyltransfer reactions at the guanine-N7 and adenosine-2'O positions. |
diagnostic usage
ongoing research
unassigned |
3
4
0 |
| 2.1.1.57 | Dengue |
19776234 |
Biochemical characterization of the (nucleoside-2'O)-methyltransferase activity of dengue virus protein NS5 using purified capped RNA oligonucleotides 7MeGpppACn and GpppACn. |
diagnostic usage
ongoing research
unassigned |
1
4
0 |
| 2.1.1.57 | Dengue |
20350738 |
Higher catalytic efficiency of N-7-methylation is responsible for processive N-7 and 2'-O methyltransferase activity in dengue virus. |
unassigned |
0 |
| 2.1.1.57 | Dengue |
22570514 |
Designing cyclopentapeptide inhibitor as potential antiviral drug for dengue virus ns5 methyltransferase. |
diagnostic usage
therapeutic application
unassigned |
3
4
0 |
| 2.1.1.57 | Dengue |
23935499 |
Rational design of a live attenuated dengue vaccine: 2'-o-methyltransferase mutants are highly attenuated and immunogenic in mice and macaques. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
3
3
0 |
| 2.1.1.57 | Dengue |
24068915 |
Correction: Rational Design of a Live Attenuated Dengue Vaccine: 2'-O-Methyltransferase Mutants Are Highly Attenuated and Immunogenic in Mice and Macaques. |
therapeutic application
unassigned |
2
0 |
