EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
1.5.3.16 | Carcinoma |
12827295 |
Induction of the PAOh1/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cells. |
causal interaction diagnostic usage ongoing research therapeutic application |
3 1 4 1 |
1.5.3.16 | Carcinoma, Hepatocellular |
29923661 |
Spermine oxidase is upregulated and promotes tumor growth in hepatocellular carcinoma. |
causal interaction diagnostic usage unassigned |
4 3 0 |
1.5.3.16 | Colitis |
29922289 |
Distinct Immunomodulatory Effects of Spermine Oxidase in Colitis Induced by Epithelial Injury or Infection. |
causal interaction ongoing research unassigned |
4 3 0 |
1.5.3.16 | Colitis, Ulcerative |
20127992 |
Increased expression and cellular localization of spermine oxidase in ulcerative colitis and relationship to disease activity. |
causal interaction ongoing research unassigned |
2 1 0 |
1.5.3.16 | Colorectal Neoplasms |
17987291 |
Polyamine catabolism in colorectal cancer cells following treatment with oxaliplatin, 5-fluorouracil and N1, N11 diethylnorspermine. |
therapeutic application unassigned |
3 0 |
1.5.3.16 | Colorectal Neoplasms |
33618627 |
The roles of microbial products in the development of colorectal cancer: a review. |
ongoing research unassigned |
2 0 |
1.5.3.16 | Diabetic Nephropathies |
16554974 |
Polyamines in renal failure. |
causal interaction diagnostic usage ongoing research therapeutic application |
1 4 2 1 |
1.5.3.16 | Diabetic Retinopathy |
31207342 |
Spermine oxidase: A promising therapeutic target for neurodegeneration in diabetic retinopathy. |
therapeutic application unassigned |
4 0 |
1.5.3.16 | Epilepsy |
31197571 |
Epileptic seizures and oxidative stress in a mouse model over-expressing spermine oxidase. |
ongoing research therapeutic application unassigned |
3 1 0 |
1.5.3.16 | Gastritis |
15574757 |
Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: implications for gastric carcinogenesis. |
causal interaction unassigned |
4 0 |