EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
6.3.2.8 | 0.0000005 |
- |
(1R,2S)-1-([4-[(5-tert-butyl-1-methyl-1H-pyrazol-3-yl)amino]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]amino)-2,3-dihydro-1H-inden-2-ol |
below, pH and temperature not specified in the publication |
743924 |
6.3.2.8 | 0.0000005 |
- |
(2R)-2-([4-[(5-tert-butyl-1-methyl-1H-pyrazol-3-yl)amino]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]amino)-2-(3-fluorophenyl)ethan-1-ol |
below, pH and temperature not specified in the publication |
743924 |
6.3.2.8 | 0.0000005 |
- |
(2R)-2-([4-[(5-tert-butyl-1-methyl-1H-pyrazol-3-yl)amino]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]amino)-2-phenylethyl [[(4S)-3-methyl-2-oxoimidazolidin-4-yl]methyl]carbamate |
below, pH and temperature not specified in the publication |
743924 |
6.3.2.8 | 0.0023 |
- |
5-methyl-N-([4-(5-phenyl-1-benzofuran-2-yl)phenyl]sulfonyl)thiophene-2-carboxamide |
Compound A, IC50 2.3 microM |
661276 |
6.3.2.8 | 0.0000007 |
- |
(2R)-2-((4-[(5-tert-butyl-1-methyl-1H-pyrazol-3-yl)amino]-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino)-3-cyclohexylpropan-1-ol |
pH 8.0, 25°C, recombinant enzyme |
744050 |
6.3.2.8 | 0.000012 |
- |
(2R)-2-((4-[(5-tert-butyl-1-methyl-1H-pyrazol-3-yl)amino]-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino)-3-cyclohexylpropan-1-ol |
pH 8.0, 25°C, recombinant enzyme |
744050 |
6.3.2.8 | 0.018 |
- |
(5Z)-5-([4-[(E)-2-phenylethenyl]phenyl]methylidene)-2-thioxo-1,3-thiazolidin-4-one |
pH 8.0, 37°C |
694288 |
6.3.2.8 | 0.027 |
- |
(5Z)-5-([2-[(4-chlorobenzyl)sulfanyl]-5-nitrophenyl]methylidene)-2-thioxo-1,3-thiazolidin-4-one |
pH 8.0, 37°C |
694288 |
6.3.2.8 | 0.027 |
- |
N-(2-([2-(2-naphthylsulfonyl)hydrazono]methyl)phenyl)-4-nitrobenzamide |
pH 8.0, 37°C |
694288 |
6.3.2.8 | 0.03 |
- |
3-bromo-N-(4-([2-(2-naphthylsulfonyl)hydrazono]methyl)phenyl)benzamide |
pH 8.0, 37°C |
694288 |