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Information on EC 6.3.2.8 - UDP-N-acetylmuramate-L-alanine ligase

for references in articles please use BRENDA:EC6.3.2.8

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IUBMB Comments

Involved in the synthesis of a cell-wall peptide in bacteria.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

Synonyms
udp-n-acetylmuramate:l-alanine ligase, murc ligase, udp-n-acetylmuramate-l-alanine ligase, udp-n-acetylmuramoyl:l-alanine ligase, udp-n-acetylmuramic acid l-alanine ligase, l-alanine adding enzyme, uridine diphosphate n-acetylmuramate:l-alanine ligase, udp-n-acetylmuramoyl-l-alanine synthetase, udp-n-acetylmuramyl:l-alanine ligase, udp-murnac:l-alanine ligase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + UDP-N-acetyl-alpha-D-muramate + L-alanine = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing), UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing), UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)