EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference  |
|---|
   3.4.23.5 | 0.00001 |
- |
pepstatin A |
IC50 less than 0.00001 mM, pH and temperature not specified in the publication |
712050 |
| 3.4.23.5 | 0.0000025 |
- |
cathepsin D inhibitor from Streptomyces sp.MBR04 |
in 0.02M sodium citrate, pH 3.0, at 37°C |
731168 |
| 3.4.23.5 | 0.000001 |
- |
pepstatin A |
IC50 of less than 1 nM, at pH 5.5 and 37°C |
731454 |
| 3.4.23.5 | 0.0000086 |
- |
N2-[N-[(2-bromo-4,5-dimethoxyphenyl)acetyl]carbamimidoyl]-3-cyclohexyl-N-(4-fluoro-3-methoxybenzyl)-D-alaninamide |
at pH 5.5 and 37°C |
731454 |
| 3.4.23.5 | 0.000024 |
- |
N2-[N-[(3,4-dimethoxyphenyl)acetyl]carbamimidoyl]-N-(4-fluoro-3-methoxybenzyl)-D-leucinamide |
at pH 5.5 and 37°C |
731454 |
| 3.4.23.5 | 0.000044 |
- |
3-cyclohexyl-N2-[N-[(3,4-dimethoxyphenyl)acetyl]carbamimidoyl]-N-[4-(1H-tetrazol-5-yl)benzyl]-D-alaninamide |
at pH 5.5 and 37°C |
731454 |
| 3.4.23.5 | 0.000058 |
- |
N-(3,4-dimethoxybenzyl)-Na-[N-[(3,4-dimethoxyphenyl)acetyl]carbamimidoyl]-D-phenylalaninamide |
at pH 5.5 and 37°C |
731454 |
| 3.4.23.5 | 0.000067 |
- |
N-(3,4-dimethoxybenzyl)-N2-[N-[(3,4-dimethoxyphenyl)acetyl]carbamimidoyl]-D-leucinamide |
at pH 5.5 and 37°C |
731454 |
| 3.4.23.5 | 0.000081 |
- |
3-cyclohexyl-N2-[N-[(3,4-dimethoxyphenyl)acetyl]carbamimidoyl]-N-[3-fluoro-4-(1H-tetrazol-5-yl)benzyl]-D-alaninamide |
at pH 5.5 and 37°C |
731454 |
| 3.4.23.5 | 0.000085 |
- |
2-bromo-N-[(2S,3S)-4-[[2-(2,4-dichlorophenyl)ethyl][3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoyl]amino]-3-hydroxy-1-(3-phenoxyphenyl)butan-2-yl]-4,5-dimethoxybenzamide |
at pH 5.5 and 37°C |
731454 |
