EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
2.7.1.33 | 0.2 |
- |
(2E)-3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]prop-2-enoic acid |
above, pH and temperature not specified in the publication |
759146 |
2.7.1.33 | 0.1 |
- |
(2E)-3-[[(2S)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]prop-2-enoic acid |
above, pH and temperature not specified in the publication |
759146 |
2.7.1.33 | 0.036 |
- |
(2Z)-3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]prop-2-enoic acid |
pH and temperature not specified in the publication |
759146 |
2.7.1.33 | 0.1 |
- |
(2Z)-3-[[(2S)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]prop-2-enoic acid |
above, pH and temperature not specified in the publication |
759146 |
2.7.1.33 | 0.0084 |
- |
1,4-dioxa-8-azaspiro[4.5]dec-8-yl[2-[(3-fluorophenyl)sulfanyl]pyridin-4-yl]methanone |
in 50 mM PIPES-NaOH (pH 7.0), 25 mM KCl, 20 mM MgCl, at 25°C |
722830 |
2.7.1.33 | 0.0004 |
- |
1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea dihydrobromide |
isoform PanK3, at pH 7.5 and 37°C |
722018 |
2.7.1.33 | 0.00257 |
- |
2-[2-(1-benzoylpiperidin-4-yl)-5-methyl-1,3-thiazol-4-yl]-N-(4-methylphenyl)acetamide |
in 50 mM PIPES-NaOH (pH 7.0), 25 mM KCl, 20 mM MgCl, at 25°C |
722830 |
2.7.1.33 | 0.05 |
0.15 |
4-(2,4-dihydroxy-3,3-dimethylbutylamido)butyric acid |
competitive inhibitor, IC50: 0.05-0.15 mM |
673027 |
2.7.1.33 | 0.00006 |
- |
acetyl-CoA |
IC50: 60 nM, competitive inhibitor with respect to ATP |
676884 |
2.7.1.33 | 0.0000625 |
- |
acetyl-CoA |
- |
686741 |