EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
    2.4.2.17 | 0.004 |
- |
1-[(5,6-diphenyl-1,2,4-triazin-3-yl)sulfanyl]-3-(1,3-thiazol-2-yl)propan-2-one |
- |
705015 |
| 2.4.2.17 | 0.0055 |
- |
4-methoxybenzyl 2-methyl-5-oxo-4,7-dithiophen-2-yl-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate |
- |
705015 |
| 2.4.2.17 | 0.006 |
- |
N-[3-[(6-nitro-1,3-benzothiazol-2-yl)amino]-3-oxo-1-phenylpropyl]benzamide |
- |
705015 |
| 2.4.2.17 | 0.0061 |
- |
L-histidine |
in the presence of 2 mM AMP, at pH 8.0 and 24°C |
758758 |
| 2.4.2.17 | 0.0068 |
- |
1-(5-phospho-beta-D-ribosyl)-ATP |
truncated long-form enzyme devoid of its regulatory domain, at pH 8.5 and 25°C |
758757 |
| 2.4.2.17 | 0.0119 |
- |
(4E)-4-[(4-chlorophenyl)(hydroxy)methylidene]-1-(pyridin-3-ylmethyl)-5-(3,4,5-trimethoxyphenyl)pyrrolidine-2,3-dione |
- |
705015 |
| 2.4.2.17 | 0.0139 |
- |
2-[(2-bromo-3,5-dinitrophenyl)carbonyl]-N-phenylhydrazinecarboxamide |
- |
705015 |
| 2.4.2.17 | 0.0301 |
- |
L-histidine |
in the absence of AMP, at pH 8.0 and 24°C |
758758 |
| 2.4.2.17 | 0.033 |
- |
L-histidine |
pH 8.5, 25°C |
721673 |
| 2.4.2.17 | 0.04 |
- |
1-(5-phospho-beta-D-ribosyl)-ATP |
wild type long-form enzyme, at pH 8.5 and 25°C |
758757 |
