EC Number |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference |
---|
2.5.1.31 | 0.0002 |
- |
(2E,6E)-farnesyl thiodiphosphate |
pH 7.5, 25°C |
637494 |
2.5.1.31 | 0.0002 |
- |
(S)-farnesyl thiopyrophosphate |
- |
637494 |
2.5.1.31 | 0.00057 |
- |
7-(2,6-dimethyl-8-diphospho-2,6-octadienyloxy)-8-methyl-4-trifluoromethyl-chromen-2-one geranyl diphosphate |
(2E,6E)-farnesyl diphosphate as a substrate, pH 7.5, 25°C |
708864 |
2.5.1.31 | 0.0054 |
- |
(2Z,6E,10E)-4-methyl-geranylgeranyl diphosphate |
potent competitive inhibitor against (2Z,6E,10E)-geranylgeranyl diphosphate, 37°C, pH 37°C |
708500 |
2.5.1.31 | 0.0058 |
- |
(2Z,6E,10E)-4-methyl-geranylgeranyl diphosphate |
noncompetitive inhibitor against isopentenyl diphosphate, 37°C, pH 37°C |
708500 |
2.5.1.31 | 0.008 |
- |
(2E,6E,10E)-4-methylfarnesyl diphosphate |
competitive inhibitor against (2Z,6E,10E)-geranylgeranyl diphosphate, 37°C, pH 37°C |
708500 |
2.5.1.31 | 0.017 |
- |
3-desmethyl (2Z,6E,10E)-geranylgeranyl diphosphate |
substrate farnesyl diphosphate, pH 7.5, 37°C |
685691 |
2.5.1.31 | 0.017 |
- |
3-desmethyl Z-geranylgeranyl diphosphate |
substrate farnesyl diphosphate, pH 7.5, 37°C |
685691 |
2.5.1.31 | 0.028 |
- |
3-desmethyl (2Z,6E,10E)-geranylgeranyl diphosphate |
substrate (Z,E,E)-geranylgeranyl diphosphate, pH 7.5, 37°C |
685691 |
2.5.1.31 | 0.028 |
- |
3-desmethyl Z-geranylgeranyl diphosphate |
substrate (Z,E,E)-geranylgeranyl diphosphate, pH 7.5, 37°C |
685691 |