EC Number |
Cofactor |
Reference |
---|
4.2.1.28 | cobamide |
role during catalysis: dissociation of C-Co bond of the coenzyme and Co-binding to substrate, effect of analogues, one binding site per enzyme molecule |
5611 |
4.2.1.28 | cobamide |
- |
5612, 5613, 5614, 5615, 5616, 5618, 5619, 5622, 5623, 5625, 5626, 5627, 5630, 5631, 5632, 5633 |
4.2.1.28 | cobamide |
slow inactivation by analogues |
5614, 5623 |
4.2.1.28 | cobamide |
mechanism of coenzyme action |
5617, 5623 |
4.2.1.28 | cobamide |
kinetic investigations with inhibitors that mimic posthomolysis intermediate of reaction, inhibitors act as competitive inhibitors with respect to coenzyme B12 |
5620 |
4.2.1.28 | cobamide |
importance of apoenzyme tertiary structure for coenzyme-substrate interaction |
5621 |
4.2.1.28 | cobamide |
coenzyme serves as intermediate hydrogen carrier |
5623 |
4.2.1.28 | cobamide |
Co2+ promotes growth during glycerol fermentation |
5624 |
4.2.1.28 | cobamide |
Km: 0.007 mM |
5626 |
4.2.1.28 | cobamide |
not involved |
5628 |