EC Number   |
Cofactor |
Reference |
|---|
    1.2.1.47 | more |
does not react with NADP+ |
691376 |
| 1.2.1.47 | NAD+ |
- |
288255, 671302, 690142, 724438, 726537, 743576, 762831, 763484 |
| 1.2.1.47 | NAD+ |
absolute requirement for |
288254 |
| 1.2.1.47 | NAD+ |
enzyme binding structure, enzyme-NAD+ crystal structure analysis, overview. NAD+ binds in the expected site at the C-termini of the beta-strands of the Rossmann fold. NAD+ forms several electrostatic interactions with the protein. The adenine ribose hydrogen bonds with Lys180. The diphosphate interacts with Trp156, Ser233, and Thr236. The nicotinamide ribose of the one complete NAD+ forms a hydrogen bond with Glu391, a residue identically conserved in the ALDH superfamily |
762675 |
| 1.2.1.47 | NAD+ |
is specific for NAD+ |
691376 |
| 1.2.1.47 | NAD+ |
required |
689379 |
| 1.2.1.47 | NADP+ |
can also be used as oxidant |
288255 |
