EC Number |
Turnover Number Minimum [1/s] |
Turnover Number Maximum [1/s] |
Substrate |
Reference |
---|
3.1.1.84 | 1.7 |
- |
cocaine |
pH 7.4, mutant enzyme Q55A |
650108 |
3.1.1.84 | 7.8 |
- |
cocaine |
pH 7.4, wild-type enzyme |
650108 |
3.1.1.84 | 9.4 |
- |
cocaethylene |
pH 7.4, wild-type enzyme |
650108 |
3.1.1.84 | 28.83 |
- |
(-)-cocaine |
mutant enzyme A199S/F227A/S287G/A328W/E441D, pH not specified in the publication, at 25°C |
716278 |
3.1.1.84 | 31.45 |
- |
cocaine |
mutant enzyme T172R/G173Q -YGRKKRRQRRR, at pH 7.4 and 37°C |
730421 |
3.1.1.84 | 32.62 |
- |
cocaine |
mutant enzyme YGRKKRRQRRR-T172R/G173Q, at pH 7.4 and 37°C |
730421 |
3.1.1.84 | 34.42 |
- |
cocaine |
mutant enzyme LMWP-T172R/G173Q, at pH 7.4 and 37°C |
730421 |
3.1.1.84 | 35.17 |
- |
cocaine |
mutant enzyme T172R/G173Q -LMWP, at pH 7.4 and 37°C |
730421 |
3.1.1.84 | 35.8 |
- |
heroin |
recombinant enzyme, pH 7.4, 37°C |
750291 |
3.1.1.84 | 36.1 |
- |
cocaine |
mutant enzyme G173Q, at pH 7.4 and 37°C |
716824 |