EC Number   |
Subunits |
Reference |
|---|
   2.7.1.153 | ? |
x * 119471, p110delta subunit, can bind the p85 adaptor subunit, calculation from nucleotide sequence |
587104 |
| 2.7.1.153 | ? |
x * 119505, calculated, x * 110000, SDS-PAGE |
640876 |
| 2.7.1.153 | ? |
x * 120000, calculated, x * 110000, SDS-PAGE |
640916 |
| 2.7.1.153 | dimer |
class I PI3Ks exist as heterodimers consisting of one of four p110 catalytic subunit isoforms and one of two families of regulatory subunit forms. PI3K class III has only one member known as Vps34 |
709907 |
| 2.7.1.153 | dimer |
PI3 kinases are heterodimers comprised of a regulatory subunit p85 and a catalytic subunit p110. Class IA subunit p110, i.e. PIK3CA, exists in three isoforms, p110alpha, p110beta, and p110gamma. All have similar structure with domains for binding to the adaptor protein subunit PIK3R1, p85, and to RAS |
707974 |
| 2.7.1.153 | dimer |
regulatory p85alpha and p85beta subunits of class IA PI3-K share near identity in the functional domains in the C-terminus, including the amino-SH2 and the carboxy-SH2 domains, which are critical for mediating association with other SH2-containing proteins as well as binding to the p110 catalytic subunit |
709930 |
| 2.7.1.153 | heterodimer |
1 * 110000, subunit p110, + 1 * 85000, subunit p85, class IA PI3K isoforms are heterodimers consisting of a catalytic subunit (p110alpha) and a smaller regulatory subunit (p85) |
737577 |
| 2.7.1.153 | heterodimer |
1 * 110000, subunit p110, + 1 * 85000, subunit p85, class IA PI3K isoforms are heterodimers consisting of a catalytic subunit (p110beta) and a smaller regulatory subunit (p85) |
737577 |
| 2.7.1.153 | heterodimer |
1 * 110000, subunit p110, + 1 * 85000, subunit p85, class IA PI3K isoforms are heterodimers consisting of a catalytic subunit (p110delta) and a smaller regulatory subunit (p85) |
737577 |
| 2.7.1.153 | heterodimer |
1* 85000, alpha-subunit, + 1 * 110000, beta-subunit |
737882 |
