EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
6.3.2.43 | more |
purified recombinant TK0278 recognizes alpha-aminoadipate (AAA) and glutamate as substrates and ligated both compounds with TK0279, an amino group carrier protein LysW in this microorganism, in an ATP-dependent manner |
Thermococcus kodakarensis |
? |
- |
- |
6.3.2.43 | more |
purified recombinant TK0278 recognizes alpha-aminoadipate (AAA) and glutamate as substrates and ligated both compounds with TK0279, an amino group carrier protein LysW in this microorganism, in an ATP-dependent manner |
Thermococcus kodakarensis JCM 12380 |
? |
- |
- |
6.3.2.43 | more |
purified recombinant TK0278 recognizes alpha-aminoadipate (AAA) and glutamate as substrates and ligated both compounds with TK0279, an amino group carrier protein LysW in this microorganism, in an ATP-dependent manner |
Thermococcus kodakarensis ATCC BAA-918 |
? |
- |
- |
6.3.2.43 | ATP + an [amino group carrier protein]-C-terminal-L-glutamate + L-2-aminoadipate |
- |
Thermococcus kodakarensis |
ADP + phosphate + an [amino group carrier protein]-C-terminal-N-(1,5-dicarboxypentan-1-yl)-L-glutamine |
- |
? |
6.3.2.43 | ATP + an [amino group carrier protein]-C-terminal-L-glutamate + L-2-aminoadipate |
the amino-group carrier protein is LysW. Determination of the crystal structure of the LysX family protein from Thermococcus kodakarensis, which catalyzes the conjugation of LysW with either alpha-aminoadipate (AAA) or glutamate, in a complex with LysW-gamma-AAA. Substrate binding structure, overview. Residues Thr196, Asn250, and Ala251 are involved in the recognition of the delta-carboxyl group of AAA |
Thermococcus kodakarensis |
ADP + phosphate + an [amino group carrier protein]-C-terminal-N-(1,5-dicarboxypentan-1-yl)-L-glutamine |
- |
? |
6.3.2.43 | ATP + [lysine-biosynthesis-protein LysW]-C-terminal-L-glutamate + L-2-aminoadipate |
- |
Thermococcus kodakarensis |
ADP + phosphate + [lysine-biosynthesis-protein LysW]-C-terminal-gamma-(L-2-aminoadip-2-yl)-L-glutamate |
- |
? |
6.3.2.43 | ATP + [lysine-biosynthesis-protein LysW]-C-terminal-L-glutamate + L-2-aminoadipate |
- |
Thermococcus kodakarensis JCM 12380 |
ADP + phosphate + [lysine-biosynthesis-protein LysW]-C-terminal-gamma-(L-2-aminoadip-2-yl)-L-glutamate |
- |
? |
6.3.2.43 | ATP + [lysine-biosynthesis-protein LysW]-C-terminal-L-glutamate + L-2-aminoadipate |
- |
Thermococcus kodakarensis ATCC BAA-918 |
ADP + phosphate + [lysine-biosynthesis-protein LysW]-C-terminal-gamma-(L-2-aminoadip-2-yl)-L-glutamate |
- |
? |
6.3.2.43 | ATP + [lysine-biosynthesis-protein LysW]-C-terminal-L-glutamate + L-glutamate |
- |
Thermococcus kodakarensis |
ADP + phosphate + [lysine-biosynthesis-protein LysW]-C-terminal-gamma-(L-glutam-2-yl)-L-glutamate |
- |
? |
6.3.2.43 | ATP + [LysW mutant E42R]-C-terminal-L-glutamate + L-2-aminoadipate |
- |
Thermococcus kodakarensis |
ADP + phosphate + [LysW mutant E42R]-C-terminal-N-(1,5-dicarboxypentan-1-yl)-L-glutamine |
- |
? |