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Results 1 - 10 of 90

EC Number	Substrates	Commentary Substrates	Organism	Products	Commentary (Products)	Reversibility
2.7.1.153	more	-	Homo sapiens	?	-	?
2.7.1.153	more	enzyme interacts with active, GTP-bound Ras	Mammalia	?	-	?
2.7.1.153	more	p110delta does not phosphorylate the p85 adaptor but instead harbors an intrinsic autophosphorylation capacity	Homo sapiens	?	-	?
2.7.1.153	more	enzyme can promote proliferation	Drosophila melanogaster	?	-	?
2.7.1.153	more	enzyme can promote proliferation	Mammalia	?	-	?
2.7.1.153	more	phosphoinositide 3-kinase and DNA synthesis	Drosophila melanogaster	?	-	?
2.7.1.153	more	phosphoinositide 3-kinase and DNA synthesis	Mammalia	?	-	?
2.7.1.153	more	phosphoinositide 3-kinase and DNA synthesis	Dictyostelium discoideum	?	-	?
2.7.1.153	more	phosphoinositide 3-kinase and DNA synthesis	Caenorhabditis elegans	?	-	?
2.7.1.153	more	enzyme is involved in the synthesis of 3-phosphoinositides. Class I phosphoinositide 3-kinases are further subdivided into class IA and IB enzymes, which signal downstream of tyrosine kinase and heterotrimeric G protein-coupled receptors, respectively. All class I phosphoinositide 3-kinase members also bind to Ras, but the role of this interaction in physiological phosphoinositide 3-kinase signalling is not entirely clear	Drosophila melanogaster	?	-	?

Results 1 - 10 of 90

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Release 2023.1 (January 2023)