EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.4.2.19 | beta-nicotinate D-ribonucleotide + diphosphate + CO2 |
- |
Sus scrofa |
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate |
- |
? |
2.4.2.19 | more |
key enzyme of NAD+ biosynthesis |
Helicobacter pylori |
? |
- |
? |
2.4.2.19 | more |
enzyme of the kynurenine pathway |
Saccharomyces cerevisiae |
? |
- |
? |
2.4.2.19 | more |
key enzyme in NAD+ biosynthesis, also plays an important role in ensuring nicotinic acid available for the synthesis of defensive pyridine alkaloids |
Nicotiana rustica |
? |
- |
? |
2.4.2.19 | more |
key enzyme in NAD+ biosynthesis, also plays an important role in ensuring nicotinic acid available for the synthesis of defensive pyridine alkaloids |
Nicotiana tabacum |
? |
- |
? |
2.4.2.19 | more |
key enzyme in NAD+ biosynthesis, also plays an important role in ensuring nicotinic acid available for the synthesis of defensive pyridine alkaloids |
Nicotiana sylvestris |
? |
- |
? |
2.4.2.19 | more |
intermediary enzyme in the de novo NAD biosynthetic pathway |
Sus scrofa |
? |
- |
? |
2.4.2.19 | more |
the recruitment of this gene for growth on phthalate gives Burkholderia cepacia an advantage over other phthalate-degrading bacteria in the environment |
Burkholderia cepacia |
? |
- |
? |
2.4.2.19 | more |
key enzyme in catabolism of quinolinate. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders |
Homo sapiens |
? |
- |
? |
2.4.2.19 | more |
essential enzyme for the de novo biosynthesis of NAD+ |
Mycobacterium tuberculosis |
? |
- |
? |