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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
4.99.1.4
sirohydrochlorin + Co2+
pH 8.0
Arabidopsis thaliana
cobalt-sirohydrochlorin + H+
-
?
4.99.1.4
sirohydrochlorin + Fe2+
-
Arabidopsis thaliana
siroheme + H+
-
?
4.99.1.4
sirohydrochlorin + Fe2+
pH 8.0
Arabidopsis thaliana
siroheme + H+
-
?
4.99.1.4
sirohydrochlorin + Fe2+
-
Paracoccus pantotrophus
siroheme + H+
-
?
4.99.1.4
precorrin-2 + Co2+
SirB, much lower specific activity than with sirohydrochlorin
Priestia megaterium
cobalt-precorrin-2 + 2 H+
-
?
4.99.1.4
sirohydrochlorin + Co2+
SirB, lower specificity for cobalt than for iron
Priestia megaterium
cobalt-sirohydrochlorin + 2 H+
-
?
4.99.1.4
sirohydrochlorin + Fe2+
-
Priestia megaterium
siroheme + H+
-
?
4.99.1.4
sirohydrochlorin + Fe2+
SirB, monofunctional ferrochelatase, higher specificity for iron over cobalt
Priestia megaterium
siroheme + 2 H+
-
?
4.99.1.4
sirohydrochlorin + Fe2+
SirB is responsible for the final step in siroheme synthesis
Priestia megaterium
siroheme + 2 H+
-
?
4.99.1.4
precorrin-2 + Co2+
SirB, much lower specific activity than with sirohydrochlorin
Priestia megaterium DSM 509
cobalt-precorrin-2 + 2 H+
-
?
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