EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
4.99.1.4 | sirohydrochlorin + Co2+ |
- |
Salmonella enterica |
cobalt-sirohydrochlorin + 2 H+ |
- |
? |
4.99.1.4 | sirohydrochlorin + Co2+ |
- |
Saccharomyces cerevisiae |
cobalt-sirohydrochlorin + 2 H+ |
- |
? |
4.99.1.4 | sirohydrochlorin + Fe2+ |
- |
Saccharomyces cerevisiae |
siroheme + H+ |
- |
? |
4.99.1.4 | sirohydrochlorin + Fe2+ |
- |
Arabidopsis thaliana |
siroheme + H+ |
- |
? |
4.99.1.4 | sirohydrochlorin + Fe2+ |
- |
Priestia megaterium |
siroheme + H+ |
- |
? |
4.99.1.4 | sirohydrochlorin + Fe2+ |
- |
Paracoccus pantotrophus |
siroheme + H+ |
- |
? |
4.99.1.4 | sirohydrochlorin + Fe2+ |
CysG structure, the multifunctional siroheme synthase CysG synthesizes siroheme from uroporphyrinogen III, CysG contains two structurally independent modules: a bismethyltransferase and a dual-function dehydrogenase-chelatase |
Salmonella enterica |
siroheme + 2 H+ |
- |
? |
4.99.1.4 | sirohydrochlorin + Fe2+ |
CysG, siroheme biosynthesis |
Salmonella enterica |
siroheme + 2 H+ |
sulfur metabolism depends on siroheme |
? |
4.99.1.4 | sirohydrochlorin + Fe2+ |
Met8p catalyzes ferrochelation during the biosynthesis of siroheme |
Saccharomyces cerevisiae |
siroheme + 2 H+ |
- |
? |
4.99.1.4 | sirohydrochlorin + Fe2+ |
Met8p catalyzes ferrochelation during the synthesis of siroheme, both ferrochelation and NAD+-dependent dehydrogenation of preccorin-2 to produce sirohydrochlorin take place in a single bifunctional active site, Asp-141 participates in both catalytic reactions, which are not linked mechanistically, mechanism |
Saccharomyces cerevisiae |
siroheme + 2 H+ |
- |
? |