EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.6.1.67 | 7,8-dihydroneopterin 3'-triphosphate + H2O |
- |
Escherichia coli |
7,8-dihydroneopterin 3'-phosphate + diphosphate |
- |
? |
3.6.1.67 | dATP + H2O |
- |
Escherichia coli |
dAMP + diphosphate |
- |
? |
3.6.1.67 | 7,8-dihydroneopterin 3'-triphosphate + H2O |
catalytic efficiency of the enzyme is far higher for dGTP |
Arabidopsis thaliana |
7,8-dihydroneopterin 3'-phosphate + diphosphate |
- |
? |
3.6.1.67 | 7,8-dihydroneopterin 3'-triphosphate + H2O |
committed step of folate synthesis in bacteria |
Escherichia coli |
7,8-dihydroneopterin 3'-phosphate + diphosphate |
- |
? |
3.6.1.67 | 7,8-dihydroneopterin 3'-triphosphate + H2O |
key enzyme in the folate pathway |
Escherichia coli |
7,8-dihydroneopterin 3'-phosphate + diphosphate |
- |
? |
3.6.1.67 | 7,8-dihydroneopterin 3'-triphosphate + H2O |
no activity against deoxynucleoside triphosphates |
Lactococcus lactis |
7,8-dihydroneopterin 3'-phosphate + diphosphate |
- |
? |
3.6.1.67 | 7,8-dihydroneopterin 3'-triphosphate + H2O |
no activity against deoxynucleoside triphosphates |
Lactococcus lactis NZ9000 |
7,8-dihydroneopterin 3'-phosphate + diphosphate |
- |
? |
3.6.1.67 | more |
no activity with ATP, GTP, dihydroneopterin phosphate, 4-nitrophenyl hosphate or diphosphate |
Escherichia coli |
? |
- |
? |
3.6.1.67 | 7,8-dihydroneopterin 3'-triphosphate + H2O |
no detectable activity with GTP, ATP, TTP, CTP, the corresponding deoxynucleoside triphosphates, 8-oxo-dGTP, NADH, NAD, diadenosine tri- or tetraphosphate, ADP-ribose, UDP-glucose, or coenzyme A (the detection limit is less than 1% of the activity with 7,8-dihydroneopterin 3'-triphosphate) |
Lactococcus lactis |
7,8-dihydroneopterin 3'-phosphate + diphosphate |
- |
? |
3.6.1.67 | 7,8-dihydroneopterin 3'-triphosphate + H2O |
no detectable activity with GTP, ATP, TTP, CTP, the corresponding deoxynucleoside triphosphates, 8-oxo-dGTP, NADH, NAD, diadenosine tri- or tetraphosphate, ADP-ribose, UDP-glucose, or coenzyme A (the detection limit is less than 1% of the activity with 7,8-dihydroneopterin 3'-triphosphate) |
Lactococcus lactis NZ9000 |
7,8-dihydroneopterin 3'-phosphate + diphosphate |
- |
? |