EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.6.1.67 | 7,8-dihydroneopterin 3'-triphosphate + H2O |
the enzyme is far more active against dGTP, 8-oxo-GTP, dTTP, and other nucleoside and deoxynucleoside 3'-triphosphates than against 7,8-dihydroneopterin 3'-triphosphate |
Arabidopsis thaliana |
7,8-dihydroneopterin 3'-phosphate + diphosphate |
- |
? |
3.6.1.67 | 7,8-dihydroneopterin 3'-triphosphate + H2O |
catalytic efficiency of the enzyme is far higher for dGTP |
Arabidopsis thaliana |
7,8-dihydroneopterin 3'-phosphate + diphosphate |
- |
? |
3.6.1.67 | 7,8-dihydroneopterin 3'-triphosphate + H2O |
- |
Escherichia coli |
7,8-dihydroneopterin 3'-phosphate + diphosphate |
- |
? |
3.6.1.67 | 7,8-dihydroneopterin 3'-triphosphate + H2O |
committed step of folate synthesis in bacteria |
Escherichia coli |
7,8-dihydroneopterin 3'-phosphate + diphosphate |
- |
? |
3.6.1.67 | 7,8-dihydroneopterin 3'-triphosphate + H2O |
key enzyme in the folate pathway |
Escherichia coli |
7,8-dihydroneopterin 3'-phosphate + diphosphate |
- |
? |
3.6.1.67 | 7,8-dihydroneopterin 3'-triphosphate + H2O |
the enzyme participates in a folate biosynthesis pathway |
Escherichia coli |
7,8-dihydroneopterin 3'-phosphate + diphosphate |
- |
? |
3.6.1.67 | dATP + H2O |
- |
Escherichia coli |
dAMP + diphosphate |
- |
? |
3.6.1.67 | more |
no activity with ATP, GTP, dihydroneopterin phosphate, 4-nitrophenyl hosphate or diphosphate |
Escherichia coli |
? |
- |
? |
3.6.1.67 | more |
the enzyme also catalyzes the hydrolysis of dATP, 8-hydroxy-dATP, dADP, and 8-hydroxy-dADP |
Escherichia coli |
? |
- |
? |
3.6.1.67 | 7,8-dihydroneopterin 3'-triphosphate + H2O |
the second step in the pterin branch of the folate synthesis pathway |
Lactococcus lactis |
7,8-dihydroneopterin 3'-phosphate + diphosphate |
- |
? |