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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
1.14.11.6
thymine + 2-oxoglutarate + O2
-
Leishmania major
5-hydroxymethyluracil + succinate + CO2
-
?
1.14.11.6
thymine + 2-oxoglutarate + O2
the telomeric repeat sequence GGGTTA is able to stimulate J synthesis, while mutated telomeric sequences (GGGTTT, GGGATT, or GGGAAA) are unable to support J synthesis
Leishmania major
5-hydroxymethyluracil + succinate + CO2
-
?
1.14.11.6
more
enzyme is responsible for the local amplification of the unusual DNA base J
Leishmania tarentolae
?
-
?
1.14.11.6
more
the enzyme is a bifunctional helicase and thymine dioxygenase
Leishmania tarentolae
?
-
?
1.14.11.6
thymine + 2-oxoglutarate + O2
-
Leishmania tarentolae
5-hydroxymethyluracil + succinate + CO2
-
?
1.14.11.6
1-ethylthymine + 2-oxoglutarate + O2
-
Neurospora crassa
? + succinate + CO2
-
?
1.14.11.6
1-ethyluracil + 2-oxoglutarate + O2
-
Neurospora crassa
? + succinate + CO2
-
?
1.14.11.6
1-methylthymine + 2-oxoglutarate + O2
-
Neurospora crassa
1-methyl-5-(hydroxymethyl)uracil + thymine + formaldehyde + succinate + CO2
-
?
1.14.11.6
1-methyluracil + 2-oxoglutarate + O2
-
Neurospora crassa
? + succinate + CO2
-
?
1.14.11.6
5-aminouracil + 2-oxoglutarate + O2
-
Neurospora crassa
? + succinate + CO2
-
?
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