EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.4.21.92 | N-succinyl-Leu-Tyr-7-amido-4-methylcoumarin + H2O |
- |
Helicobacter pylori |
N-succinyl-Leu-Tyr + 7-amino-4-methylcoumarin |
- |
? |
3.4.21.92 | N-succinyl-Leu-Tyr-7-amido-4-methylcoumarin + H2O |
throughout the 5 min time course, ClpP readily degrades the dipeptide, whereas ClpP3/R does not. Prolonging the incubation time with ClpP3/R to 20 min does not result in any visible degradation. Addition of ClpC to the assays also fails to produce any degradation |
Synechococcus elongatus |
N-succinyl-Leu-Tyr + 7-amino-4-methylcoumarin |
- |
? |
3.4.21.92 | N-succinyl-Val-Lys-Met-7-amido-4-methylcoumarin + H2O |
throughout the 5 min time course, ClpP readily degrades the dipeptide, whereas ClpP3/R does not. Prolonging the incubation time with ClpP3/R to 20 min does not result in any visible degradation. Addition of ClpC to the assays also fails to produce any degradation |
Synechococcus elongatus |
N-succinyl-Val-Lys-Met + 7-amino-4-methylcoumarin |
- |
? |
3.4.21.92 | Arc-ssrA + H2O |
Arc repressor with a C-terminal ssrA tag |
Escherichia coli |
peptides |
- |
? |
3.4.21.92 | casein + H2O |
- |
Escherichia coli |
small peptides derived from casein |
- |
? |
3.4.21.92 | casein + H2O |
alpha-casein |
Escherichia coli |
small peptides derived from casein |
- |
? |
3.4.21.92 | casein + H2O |
- |
Escherichia coli RGC125 (lon-) |
small peptides derived from casein |
- |
? |
3.4.21.92 | Succinyl-Ala-Ala-Phe 4-methylcoumarin 7-amide + H2O |
ClpP subunit alone |
Escherichia coli |
Succinyl-Ala-Ala + Phe 4-methylcoumarin 7-amide |
- |
? |
3.4.21.92 | Succinyl-Ala-Ala-Phe 4-methylcoumarin 7-amide + H2O |
ClpP subunit alone |
Escherichia coli RGC125 (lon-) |
Succinyl-Ala-Ala + Phe 4-methylcoumarin 7-amide |
- |
? |
3.4.21.92 | succinyl-L-Leu-L-Tyr-7-amido-4-methylcoumarin + H2O |
recombinant ClpP does not cleave the known ClpP substrate succinyl-L-Leu-L-Tyr-7-amido-4-methylcoumarin |
Plasmodium falciparum |
succinyl-L-Leu-L-Tyr + 7-amino-4-methylcoumarin |
- |
? |