EC Number   |
Substrates  |
Organism |
Products |
Reversibility |
|---|
   2.1.1.56 | more |
the enzyme is responsible for guanine-N7 methylation of recapped mRNAs |
Homo sapiens |
? |
- |
- |
| 2.1.1.56 | more |
no activity with 7mGpppA |
Homo sapiens |
? |
- |
- |
| 2.1.1.56 | more |
no activity with 7mGpppA |
Severe acute respiratory syndrome-related coronavirus |
? |
- |
- |
| 2.1.1.56 | more |
the protein reveals cap-independent methyltransferase activities targeting internal adenosine residues. Besides this, the enzyme domain also methylates the N7 position of the cap guanosine. The enzyme preferentially methylates adenosine residues and is not active on poly G, C and U RNAs |
Sudan ebolavirus |
? |
- |
- |
| 2.1.1.56 | more |
ATP, XTP, CTP, UTP, and guanosine containing compounds with phospho groups in either position 2' or 3' or in 3'-5'phosphodiester linkage |
Vaccinia virus WR |
? |
- |
? |
| 2.1.1.56 | more |
no substrates are poly-(A) terminating in a single phosphate or a diphosphate |
Vaccinia virus WR |
? |
- |
? |
| 2.1.1.56 | S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] |
- |
Homo sapiens |
S-adenosyl-L-homocysteine + a 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] |
- |
? |
| 2.1.1.56 | S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] |
- |
Murine hepatitis virus |
S-adenosyl-L-homocysteine + a 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] |
- |
? |
| 2.1.1.56 | S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] |
- |
Severe acute respiratory syndrome-related coronavirus |
S-adenosyl-L-homocysteine + a 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] |
- |
? |
| 2.1.1.56 | S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] |
the enzyme methylates the guanosine cap on the N-7 position to create the cap structure, m7G(5)ppp(5)X |
Homo sapiens |
S-adenosyl-L-homocysteine + a 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] |
- |
? |
