EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    1.14.14.18 | gamma-CH-Fe(cor) + 3 AH2 + 3 O2 |
the regioisomeric iron corrole is an artificial, not-natural substrate, the enzymatic cleavage happens selectively at the unexpected bipyrrolic position and yields a biomimetic biliverdin-like product. The enzymatic corrole ring opening is selective for this corrole regioisomer and for plant-type heme oxygenase, mechanism, overview |
Synechocystis sp. |
? |
- |
? |
| 1.14.14.18 | gamma-meso-hydroxyhemin IX + reduced acceptor + O2 |
- |
Rattus norvegicus |
verdoheme IXgamma + CO + acceptor + H2O |
- |
? |
| 1.14.14.18 | hematoheme + NADPH + H+ + O2 |
- |
Rattus norvegicus |
hematobiliverdin Fe2+ + CO + NAD+ + H2O |
- |
r |
| 1.14.14.18 | heme + 2 NADH + 2 H+ + 2 O2 |
NADH-dependent heme degradation system may have a biological role in regulating the concentration of respiratory hemoproteins and the disposition of the aberrant forms of the mitochondrial hemoproteins |
Bos taurus |
biliverdin + Fe2+ + CO + 2 NAD+ + H2O |
- |
? |
| 1.14.14.18 | heme + 2 NADPH + 2 H+ + 2 O2 |
- |
Gallus gallus |
biliverdin + Fe2+ + CO + 2 NADP+ + H2O |
- |
? |
| 1.14.14.18 | heme + 2 NADPH + 2 H+ + 2 O2 |
- |
Homo sapiens |
biliverdin + Fe2+ + CO + 2 NADP+ + H2O |
- |
? |
| 1.14.14.18 | heme + 2 NADPH + 2 H+ + 2 O2 |
- |
Rattus norvegicus |
biliverdin + Fe2+ + CO + 2 NADP+ + H2O |
- |
? |
| 1.14.14.18 | heme + 2 NADPH + 2 H+ + 2 O2 |
- |
Bos taurus |
biliverdin + Fe2+ + CO + 2 NADP+ + H2O |
- |
? |
| 1.14.14.18 | heme + 2 NADPH + 2 H+ + 2 O2 |
involved in heme metabolism |
Gallus gallus |
biliverdin + Fe2+ + CO + 2 NADP+ + H2O |
- |
? |
| 1.14.14.18 | heme + 2 NADPH + 2 H+ + 2 O2 |
involved in heme metabolism |
Homo sapiens |
biliverdin + Fe2+ + CO + 2 NADP+ + H2O |
- |
? |
