EC Number   |
Substrates |
Organism  |
Products |
Reversibility |
|---|
   6.5.1.3 | ATP + (ribonucleotide)n-3'-hydroxyl + 5'-phospho-(ribonucleotide)m |
- |
Methanothermobacter thermautotrophicus |
(ribonucleotide)n+m + AMP + diphosphate |
- |
? |
| 6.5.1.3 | ATP + [RNA ligase]-L-lysine |
- |
Methanothermobacter thermautotrophicus |
[RNA ligase]-N6-(5'-adenylyl)-L-lysine + diphosphate |
- |
? |
| 6.5.1.3 | more |
enzyme does not discriminate between RNA and DNA for phosphodiester bond formation |
Methanothermobacter thermautotrophicus |
? |
- |
? |
| 6.5.1.3 | more |
intramolecular ligation of 5'-PO4 single-strand RNA to form a covalently closed circular RNA molecule through ligase-adenylylate and RNA-adenylylate intermediates AppRNA. At the optimal temperature of 65°C, AppRNA is predominantly ligated to a circular product. At 35°C, phosphodiester bond formation is suppressed and the majority of the AppRNA is deadenylylated |
Methanothermobacter thermautotrophicus |
? |
- |
? |
| 6.5.1.3 | more |
the enzyme catalyzes an adenylation reaction that is specific for ATP and either ssDNA or RNA. It does not require synthesis of a template strand for adenylation. To achieve quantitative DNA adenylation, single turnover reaction condition with substrate to enzyme ratio 1:1 should be used |
Methanothermobacter thermautotrophicus |
? |
- |
? |
| 6.5.1.3 | more |
the enzyme catalyzes formation of phosphodiester bonds between the 5'-phosphate and 3'-hydroxyl termini of single-stranded RNAs. It can also react with RNA with a 3'-phosphate end to generate a 2',3'-cyclic phosphate. The enzyme can additionally remove adenosine from the 3'-terminus of the RNA to produce 3'-deadenylated RNA |
Methanothermobacter thermautotrophicus |
? |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n-3'-hydroxyl + 5'-phospho-(ribonucleotide)m |
- |
Methanothermobacter thermautotrophicus ATCC 29096 |
(ribonucleotide)n+m + AMP + diphosphate |
- |
? |
| 6.5.1.3 | ATP + [RNA ligase]-L-lysine |
- |
Methanothermobacter thermautotrophicus ATCC 29096 |
[RNA ligase]-N6-(5'-adenylyl)-L-lysine + diphosphate |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n-3'-hydroxyl + 5'-phospho-(ribonucleotide)m |
- |
Naegleria gruberi |
(ribonucleotide)n+m + AMP + diphosphate |
- |
? |
| 6.5.1.3 | ATP + [RNA ligase]-L-lysine |
- |
Naegleria gruberi |
[RNA ligase]-N6-(5'-adenylyl)-L-lysine + diphosphate |
- |
? |
