EC Number |
Source Tissue |
Reference |
---|
3.5.1.109 | epidermis |
- |
712591 |
3.5.1.109 | epidermis |
in extracts of whole epidermis biopsies from patients with atopic dermatitis, sphingomyelin deacylase activities are significantly (3-fold) increased over healthy controls in the particulate fraction, whereas there is no significant difference in the activity of sphingomyelinase between atopic dermatitis and healthy control |
712668 |
3.5.1.109 | epidermis |
of patients with atopic dermatitis |
711127 |
3.5.1.109 | epidermis |
upregulation in epidermis of patients with atopic dermatitis |
712912 |
3.5.1.109 | lymphocyte |
in peripheral blood lymphocytes of patients with atopic dermatitis, there is no increase in activity compared with healthy controls |
712668 |
3.5.1.109 | stratum corneum |
activity is enhanced more than 5fold in involved stratum corneum, more than 3fold in uninvolved stratum corneum, and approximately 3fold in the involved epidermis from patients with atopic dermatitis compared with healthy controls |
712591 |
3.5.1.109 | stratum corneum |
from lesional forearm skin (volar side) of patients with atopic dermatitis, sphingomyelin deacylase activity is at least 5times higher than in the stratum corneum of healthy controls. In stratum corneum from nonlesional skin of patients with atopic dermatitis, SM deacylase activity is at least three times higher than in healthy controls. Stratum corneum from contact dermatitis patients shows levels of sphingomyelin deacylase similar to healthy controls |
712668 |
3.5.1.109 | stratum corneum |
of patients with atopic dermatitis |
711127 |
3.5.1.109 | stratum corneum |
upregulation in stratum corneum of patients with atopic dermatitis |
712912 |