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Literature summary for 3.5.1.109 extracted from

  • Ishibashi, M.; Arikawa, J.; Okamoto, R.; Kawashima, M.; Takagi, Y.; Ohguchi, K.; Imokawa, G.
    Abnormal expression of the novel epidermal enzyme, glucosylceramide deacylase, and the accumulation of its enzymatic reaction product, glucosylsphingosine, in the skin of patients with atopic dermatitis (2003), Lab. Invest., 83, 397-408.
    View publication on PubMed
Search for more literature for 3.5.1.109

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N-palmitoyl-sphingosylphosphorylcholine + H2O Homo sapiens
-
 palmitic acid + sphingosylphosphorylcholine
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epidermis upregulation in epidermis of patients with atopic dermatitis Homo sapiens
-
stratum corneum upregulation in stratum corneum of patients with atopic dermatitis Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-palmitoyl-sphingosylphosphorylcholine + H2O
-
 Homo sapiens palmitic acid + sphingosylphosphorylcholine
-
 ?

Synonyms

Synonyms Comment Organism
GC deacylase
-
 Homo sapiens
glucosylceramide deacylase
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Homo sapiens

Expression

Organism Comment Expression
Homo sapiens upregulation in epidermis and stratum corneum of patients with atopic dermatitis up