EC Number   |
General Information |
Reference |
|---|
   7.4.2.6 | malfunction |
aknockout mutant shows marked impairment in its capacity to persist in the respiratory tract compared to the wild type in a mouse pulmonary clearance model |
-, 733968 |
| 7.4.2.6 | malfunction |
loss of enzyme function abrogates spirochete growth in vitro |
-, 751458 |
| 7.4.2.6 | malfunction |
mutations in OppA transport domain result in Mycobacterium avium impairment in macrophages and in mice |
734630 |
| 7.4.2.6 | more |
Genes Mtb Rv3666c-Rv3663c encode an Opp transport system dispensable for in vitro growth. The Opp loss of function mutant shows no in vitro growth defect, but has diminished burden during chronic infection and produces a slightly delayed time to death of animals when compared to wild-type infection. But disruption of the opp locus affects the expression of genes involved in the production of mycobacterial lipids |
711957 |
| 7.4.2.6 | more |
morphology of wild type and cgopt1 mutants in presence or absence of iodoacetic acid, overview |
711605 |
| 7.4.2.6 | more |
transcription of the bldK-g operon is affected by adpA deletion, but appears not to be directly regulated by AdpA |
-, 719524 |
| 7.4.2.6 | physiological function |
bldK, a gene cluster that encodes the components of an oligopeptide permease family of the ATP-binding cassette transporter, shows direct involvement in the extracellular signaling |
-, 719524 |
| 7.4.2.6 | physiological function |
CgOPT1 is involved in regulation of fungal response to iodoacetic acid, and is also necessary for full virulence, but it is unclear whether this phenotype is related to auxin. CgOpt1 is probably associated only with light-dependent sporulation, and is not required for light-independent sporulation |
711605 |
| 7.4.2.6 | physiological function |
PepT1 is an integral plasma membrane protein responsible for the uptake of dietary di- and tripeptides in cells. It transports peptides against a concentration gradient in a pH-dependent manner. PepT1 transporter is electrogenic |
713195 |
| 7.4.2.6 | physiological function |
ScOPT1 is a high affinity GSH transporter. Fungal OPTs function in nutrient uptake from the environment |
713255 |
