EC Number   |
General Information |
Reference |
|---|
    4.2.1.1 | evolution |
carbonic anhydrase is a member of zinc-containing metalloenzyme family |
747662 |
| 4.2.1.1 | evolution |
carbonic anhydrase represents one of the most ancient proteins |
716443 |
| 4.2.1.1 | evolution |
comparisons of putative active site residues between CA II and CA VI from humans and several fishes |
747901 |
| 4.2.1.1 | evolution |
evolutionary relationship analysis, phylogenetic tree, the enzyme belongs to the beta class of carbonic anhydrases, subgroup of type II beta-CAs. The enzyme B13-CA has all the features of a catalytically effective beta-CA: (i) the putative Zn(II) ligands, Cys42, Asp44, His 98 and Cys101, (ii) the catalytic dyad involved in activation of the zinc-coordinated water molecule/hydroxide ion for catalysis, represented by the Asp44-Arg46 residues, which resembles in a way the activation of the water molecule in aspartic proteases |
748305 |
| 4.2.1.1 | evolution |
evolutionary tree of some bacterial beta-CAs among which the two Brucella suis isozymes bsCA I and bsCA II, phylogenetic analysis, overview |
-, 714456 |
| 4.2.1.1 | evolution |
HICA is a type II member of the beta-carbonic anhydrase family |
714191 |
| 4.2.1.1 | evolution |
phylogenetic analysis indicates that Pl-CAN is evolutionarily closer to humans among chordates than to other species |
748524 |
| 4.2.1.1 | evolution |
phylogenetic analysis of beta-class carbonic anhydrases in invertebrates, overview |
714606 |
| 4.2.1.1 | evolution |
phylogenetic tree of gamma-CAs |
747272 |
| 4.2.1.1 | evolution |
several genetically distinct classes of carbonic anhydrase (CAs) exist, e.g. alpha-, beta-, gamma-, delta- and zeta-, and all of them are metalloenzymes. delta-CAs are closer to the alpha-CAs than to the other classes of the enzymes, phylogenetic analysis |
748302 |
