Cloned (Comment) | Organism |
---|---|
isozyme carbonic anhydrase 6, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis and tree, quantitative real-time PCR and quantitative/semiquantitative RT-PCR expression analysis | Takifugu rubripes |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | the isozyme VI is secreted | Takifugu rubripes | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | required, metalloenzyme | Takifugu rubripes |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
H2CO3 | Takifugu rubripes | - |
CO2 + H2O | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Takifugu rubripes | A0A2D1CFJ9 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | isozyme CA VI contains three potential N-linked glycosylation sites | Takifugu rubripes |
additional information | two cysteine residues, Cys28 and Cys209, that are likely to form one disulfide bond, are present in pufferfish CA VI | Takifugu rubripes |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | the pufferfish CA VI is highly expressed in liver tissue | Takifugu rubripes | - |
additional information | quantitative and semiquantitative RT-PCR expression analysis and in situ hybridization | Takifugu rubripes | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
H2CO3 | - |
Takifugu rubripes | CO2 + H2O | - |
r |
Subunits | Comment | Organism |
---|---|---|
More | three-dimensional homology structure modeling of carbonic anhydrase VI, overview | Takifugu rubripes |
Synonyms | Comment | Organism |
---|---|---|
CA VI | - |
Takifugu rubripes |
carbonic anhydrase 6 | - |
Takifugu rubripes |
carbonic anhydrase VI | - |
Takifugu rubripes |
secretory carbonic anhydrase VI | - |
Takifugu rubripes |
General Information | Comment | Organism |
---|---|---|
evolution | comparisons of putative active site residues between CA II and CA VI from humans and several fishes | Takifugu rubripes |
additional information | homology modeling of puffer CA VI is performed using the crystal structure of human carbonic anhydrase XIV as a template structure | Takifugu rubripes |
physiological function | pufferfish CA VI is an extracellular secretory protein | Takifugu rubripes |