EC Number   |
General Information |
Reference  |
|---|
   1.4.4.2 | physiological function |
part of glycine cleavage system |
706478 |
| 1.4.4.2 | metabolism |
glycine decarboxylase is a major enzyme that is involved in the C1 metabolism of all organisms and in the photorespiratory pathway of plants and cyanobacteria. GCS is also essential in the plant photorespiratory C2 cycle, which salvages 2-phosphoglycolate resulting from the oxygenation reaction catalysed by ribulose-1,5-bisphosphate carboxylase/oxygenase under atmospheric conditions. The complete GCS reaction cycle requires the cooperation of three different enzymes, P-protein, T-protein and L-protein, and the small heat-stable H-protein, pathway overview |
710748 |
| 1.4.4.2 | more |
glycine decarboxylase, or P-protein, is part of the glycine cleavage system, GCS |
710748 |
| 1.4.4.2 | metabolism |
the glycine decarboxylase complex, GDC, is a key enzyme of the photorespiratory C2 cycle in C3 plants, regulation of plant glycine decarboxylase by S-nitrosylation and glutathionylation, overview. GDC activity is inhibited by S-nitrosoglutathione due to S-nitrosylation/S-glutathionylation of several cysteine residues |
713311 |
| 1.4.4.2 | more |
the mitochondrial photorespiratory system is involved in the regulation of NO signal transduction in Arabidopsis thaliana |
713311 |
| 1.4.4.2 | physiological function |
role of GDC in the harpin-induced plant defense response, overview |
713311 |
| 1.4.4.2 | physiological function |
the H-protein interacts with the L-protein, which is also part of the L-ketoglutarate dehydrogenase complex |
724197 |
| 1.4.4.2 | physiological function |
enzyme overexpression promotes glycolysis, serine/glycine metabolism, and the accumulation of pyrimidine nucleotides. Enzyme overexpression alone is able to transform NIH 3T3 cells in vitro and drive tumor formation in vivo |
724693 |
| 1.4.4.2 | physiological function |
overexpression of the H-protein of glycine decarboxylase considerably enhances net-photosynthesis and growth of Arabidopsis thaliana. Glycine decarboxylase is an important feed-back signaller that contributes to the control of the Calvin-Benson cycle and hence carbon flow through both photosynthesis and photorespiration |
725016 |
| 1.4.4.2 | physiological function |
glycine decarboxylase is an unusual amino acid decarboxylase involved in tumorigenesis. In humans, GLDC is part of a multienzyme complex (which includes the lipoyl-containing H-protein) that couples the decarboxylation of glycine to the biosynthesis of serine |
741906 |
