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EC Number Expression Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.1down Dyrk1A expression can be reressed by the AP4- geminin complex 703132
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.1up Dyrk1A expression can be enhanced by treatment with beta-amyloid or overexpression of the transcription factor E2F1, Dyrk1A activity can be increased by binding of 14-3-3 protein 703132
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.1up the enzyme is upregulated in cells expressing the high-risk human papillomavirus E7 oncogene, which promotes S-phase entry of host cells from quiescent state in the presence of elevated cell cycle inhibitor p27Kip1 741084
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.1up there are higher levels of full-length DYRK1A in the brains of patients with Down syndrome when compared to control brains 701564
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.1up TTK kinase is upregulated in pancreatic cancer 740243
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