EC Number   |
Expression |
Reference |
|---|
    2.7.1.21 | down |
0.001 mM of the mitogenic extracellular kinase 1/2 inhibitor PD0325901 rapidly decreases thymidine kinase 1 protein levels and mRNA expression in SKMEL-28 human melanoma cells with maximum reduction at 48 h posttreatment |
705660 |
| 2.7.1.21 | down |
trifluridine and 5-fluoro-2'-deoxyuridine lead to concentration dependent reduction of thymidine kinase 1 expression |
759869 |
| 2.7.1.21 | up |
DNA damage causes up-regulation of thymidine kinase 1 in tumor cells |
722681 |
| 2.7.1.21 | up |
doxorubicin treatment leads to upregulation of thymidine kinase 1 |
759869 |
| 2.7.1.21 | up |
treatment with hydrogen peroxide results in induction of thymidine kinase 1, however, the thymidine kinase 1 activity does not correlate with thymidine kinase 1 protein levels, indicating that TK1 protein is inactive |
759869 |
| 2.7.1.21 | up |
upregulated after araC and dFdC treatment |
759869 |
