Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5-fluoro-2'-deoxyuridine | concentration dependent reduction of activity | Homo sapiens | |
trifluridine | concentration dependent reduction of activity | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P04183 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
thymidine kinase 1 | - |
Homo sapiens |
TK1 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | trifluridine and 5-fluoro-2'-deoxyuridine lead to concentration dependent reduction of thymidine kinase 1 expression | down |
Homo sapiens | doxorubicin treatment leads to upregulation of thymidine kinase 1 | up |
Homo sapiens | treatment with hydrogen peroxide results in induction of thymidine kinase 1, however, the thymidine kinase 1 activity does not correlate with thymidine kinase 1 protein levels, indicating that TK1 protein is inactive | up |
Homo sapiens | upregulated after araC and dFdC treatment | up |