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EC Number
BRENDA No.
Title
Journal
Volume
Pages
Year
Organism
PubMed ID
3.4.22.51
700875
RNA interference of Trypanosoma brucei cathepsin B and L affects disease progression in a mouse model
PLoS Negl. Trop. Dis.
2
e298
2008
Trypanosoma brucei
18820745
3.4.22.51
696645
Synthesis of macrocyclic trypanosomal cysteine protease inhibitors
Bioorg. Med. Chem. Lett.
18
5860-5863
2008
Trypanosoma brucei rhodesiense
18585034
3.4.22.51
638884
Congopain from Trypanosoma congolense: drug target and vaccine candidate
Biol. Chem.
383
739-749
2002
Trypanosoma congolense
12108538
3.4.22.51
710673
Modulation of the immunogenicity of the Trypanosoma congolense cysteine protease, congopain, through complexation with alpha2-macroglobulin
Vet. Res.
40
52
2009
Trypanosoma congolense
19549486
3.4.22.51
752781
Catalytic mechanism of cruzain from Trypanosoma cruzi as determined from solvent kinetic isotope effects of steady-state and pre-steady-state kinetics
Biochemistry
57
3176-3190
2018
Trypanosoma cruzi
29336553
3.4.22.51
752406
Cruzain structures apocruzain and cruzain bound to S-methyl thiomethanesulfonate and implications for drug design
Acta Crystallogr. Sect. F
75
419-427
2019
Trypanosoma cruzi
31204688
3.4.22.51
755082
Cruzipain activates latent TGF-beta from host cells during T. cruzi invasion
PLoS ONE
10
e0124832
2015
Trypanosoma cruzi
25938232
3.4.22.51
753013
Evaluation of quinoxaline compounds as ligands of a site adjacent to S2 (AS2) of cruzain
Bioorg. Med. Chem. Lett.
29
2197-2202
2019
Trypanosoma cruzi
31257083
3.4.22.51
755010
Experimental study and computational modelling of cruzain cysteine protease inhibition by dipeptidyl nitriles
Phys. Chem. Chem. Phys.
20
24317-24328
2018
Trypanosoma cruzi
30211406
3.4.22.51
752755
First quantum mechanics/molecular mechanics studies of the inhibition mechanism of cruzain by peptidyl halomethyl ketones
Biochemistry
54
3381-3391
2015
Trypanosoma cruzi
25965914
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