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EC Number
BRENDA No.
Title
Journal
Volume
Pages
Year
Organism
PubMed ID
3.4.22.51
755082
Cruzipain activates latent TGF-beta from host cells during T. cruzi invasion
PLoS ONE
10
e0124832
2015
Trypanosoma cruzi
25938232
3.4.22.51
753481
Synthesis and structure-activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain
Eur. J. Med. Chem.
101
818-835
2015
Trypanosoma cruzi
26231082
3.4.22.51
755010
Experimental study and computational modelling of cruzain cysteine protease inhibition by dipeptidyl nitriles
Phys. Chem. Chem. Phys.
20
24317-24328
2018
Trypanosoma cruzi
30211406
3.4.22.51
753923
In silico analysis of homologous heterodimers of cruzipain-chagasin from structural models built by homology
Int. J. Mol. Sci.
20
E1320
2019
Trypanosoma cruzi
30875920
3.4.22.51
753924
Structure-based virtual screening and in vitro evaluation of new Trypanosoma cruzi cruzain inhibitors
Int. J. Mol. Sci.
20
E1742
2019
Trypanosoma cruzi
30970549
3.4.22.51
753924
Structure-based virtual screening and in vitro evaluation of new Trypanosoma cruzi cruzain inhibitors
Int. J. Mol. Sci.
20
E1742
2019
Trypanosoma cruzi INC-5
30970549
3.4.22.51
753013
Evaluation of quinoxaline compounds as ligands of a site adjacent to S2 (AS2) of cruzain
Bioorg. Med. Chem. Lett.
29
2197-2202
2019
Trypanosoma cruzi
31257083
3.4.22.51
752755
First quantum mechanics/molecular mechanics studies of the inhibition mechanism of cruzain by peptidyl halomethyl ketones
Biochemistry
54
3381-3391
2015
Trypanosoma cruzi
25965914
3.4.22.51
752781
Catalytic mechanism of cruzain from Trypanosoma cruzi as determined from solvent kinetic isotope effects of steady-state and pre-steady-state kinetics
Biochemistry
57
3176-3190
2018
Trypanosoma cruzi
29336553
3.4.22.51
752406
Cruzain structures apocruzain and cruzain bound to S-methyl thiomethanesulfonate and implications for drug design
Acta Crystallogr. Sect. F
75
419-427
2019
Trypanosoma cruzi
31204688
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