6.3.2.8 | phosphoprotein |
MurC is phosphorylated in vitro by the PknA protein kinase, but not by PknG kinase, exclusively on threonine residues, which has regulatory function, mutation of the phosphorylation site threonine residues impairs enzyme activity, double phosphorylation of the activation loop residues Thr179 and Thr181 is necessary for full kinase activity |
693199 |