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EC Number
Application
Commentary
Reference
5.1.1.17
biotechnology
production of beta-lactam antibiotics
700004
5.1.1.17
biotechnology
The results indicate that Penecillium chrysogenum can be used as heterologous host for the production of deacetylcephalosporin C
673028
5.1.1.17
medicine
the conversion of isopenicillin N into penicillin N is part of the cephalosporin biosynthesis pathway. Cephalosporin is one of the most potent beta-lactam antibiotics, widely used in the treatment of infectious diseases
660640
5.1.1.17
synthesis
epimerization is a rate-limiting step in cephalosporin biosynthesis in Acremonium chrysogenum. When epimerase activity is enhanced, there is a clear increase in cephalosporin production. Thus, this method provides a strategy that could easily be applied to improve industrial cephalosporin producing strains
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662877
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