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Literature summary for 5.1.1.17 extracted from
- Novel genes involved in cephalosporin biosynthesis: the three-component isopenicillin N epimerase system (2004), Adv. Biochem. Eng. Biotechnol., 88, 91-109.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | the conversion of isopenicillin N into penicillin N is part of the cephalosporin biosynthesis pathway. Cephalosporin is one of the most potent beta-lactam antibiotics, widely used in the treatment of infectious diseases | Acremonium chrysogenum |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| isopenicillin N | Acremonium chrysogenum | - |
penicillin N | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Acremonium chrysogenum | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| isopenicillin N | - |
Acremonium chrysogenum | penicillin N | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| isopenicillin N epimerase | - |
Acremonium chrysogenum |
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Release 2023.1 (January 2023)
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