EC Number |
Application |
Reference |
---|
3.4.22.47 | medicine |
development of potent, gingipain-specific inhibitors might be a helpful tool in a therapeutic strategy to prevent or treat periodontal disease |
699738 |
3.4.22.47 | medicine |
development of structure-based inhibitors for treatment of periodontal diseases |
-, 669799 |
3.4.22.47 | medicine |
results indicate that degradation of apoB-100 by Rgp but not Kgp plays a crucial role in the promotion of atherosclerosis by Porphyromonas gingivalis infection |
680547 |
3.4.22.47 | molecular biology |
a combination of both R- and K-gingipains is required for pigment production from oxyhemoglobin by Porphyromonas gingivalis since R-gingipain converts oxyhemoglobin into the methemoglobin form which is more susceptible to Kgp degradation for the eventual release of iron(III) protoporphyrin IX and production of the micro-oxo haem dimer |
-, 677827 |
3.4.22.47 | molecular biology |
it is shown that the production of anionic polysaccharide at the surface of Porphyromonas gingivalis rather than Arg- and Lys-gingipain synthesis is the principal mechanism of serum resistance in Porphyromonas gingivalis |
680131 |