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Literature summary for 3.4.22.47 extracted from
- Selective proteolysis of apolipoprotein B-100 by Arg-gingipain mediates atherosclerosis progression accelerated by bacterial exposure (2006), J. Biochem., 140, 713-723.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | results indicate that degradation of apoB-100 by Rgp but not Kgp plays a crucial role in the promotion of atherosclerosis by Porphyromonas gingivalis infection | Porphyromonas gingivalis |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | strains: Rgp/Kgp-null (rgpA rgpB kgpdeficient) triple-mutant KDP136 and the Kgp-null mutant (KDP129) | Porphyromonas gingivalis |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| KYT-36 | specific inhibitor for Kgp | Porphyromonas gingivalis |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Porphyromonas gingivalis | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| KGP | - |
Porphyromonas gingivalis |
| Lys-gingipain | - |
Porphyromonas gingivalis |
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Release 2023.1 (January 2023)
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