EC Number   |
Metals/Ions |
Reference |
|---|
   3.4.11.3 | Zn2+ |
2 mol Zn2+ per subunit |
35900 |
| 3.4.11.3 | Zn2+ |
active site-bound |
754389 |
| 3.4.11.3 | Zn2+ |
complete inhibition of the enzyme activity by 0.1 mM EDTA and 0.1 mM 1,10-phenanthroline can be prevented in the presence of 0.04-0.1 mM ZnCl2 |
667549 |
| 3.4.11.3 | Zinc |
contains the characteristic Zn2+-coordination sequence element, HEXXH-(18-64X)-E |
651116 |
| 3.4.11.3 | Zinc |
enzyme contains 1 mol of zinc per mol of enzyme, contains the consensus HEXXH(X)18E motif of zinc-metallopeptidase proteins |
651074 |
| 3.4.11.3 | Co2+ |
inhibition at high concentration |
35898, 35908, 35910 |
| 3.4.11.3 | Ca2+ |
inhibitory effect of EDTA plus 1,10-phenanthroline can be completely reversed by Zn2+. Ca2+ and Mg2+ increase the potency of Zn2+ for this process |
667507 |
| 3.4.11.3 | Mg2+ |
inhibitory effect of EDTA plus 1,10-phenanthroline can be completely reversed by Zn2+. Ca2+ and Mg2+ increase the potency of Zn2+ for this process |
667507 |
| 3.4.11.3 | Zn2+ |
inhibitory effect of EDTA plus 1,10-phenanthroline can be completely reversed by Zn2+. Ca2+ and Mg2+ increase the potency of Zn2+ for this process |
667507 |
| 3.4.11.3 | Zn2+ |
insulin-regulated aminopeptidase (IRAP) is a membrane-bound zinc metallopeptidase |
752375 |
