EC Number |
Metals/Ions |
Reference |
---|
4.2.1.2 | Mg2+ |
about 20fold activation of isoform Fum1 |
749006 |
4.2.1.2 | Mg2+ |
cytosolic form gets strongly activated, mitochondrial form only moderately activated |
730558 |
4.2.1.2 | Mg2+ |
required, stimulates 10% at 5 mM |
716122 |
4.2.1.2 | Mn2+ |
15fold activation of isoform Fum2 |
749006 |
4.2.1.2 | Mn2+ |
cytosolic form gets strongly activated, mitochondrial form only less effectively activated |
730558 |
4.2.1.2 | more |
activity does not increase upon incubation with Fe2+ |
749072 |
4.2.1.2 | more |
aluminium and gallium do not perturb the activity of fumarase C |
695741 |
4.2.1.2 | more |
class II fumarase activity is frequently influenced by divalent metal ions and non-ionic surfactants. No effect by Ca2+ |
716122 |
4.2.1.2 | more |
no effects of Zn2+, Fe2+, or EDTA on enzyme activity |
715093 |
4.2.1.2 | more |
not activating: Ca2+, K+ |
749006 |